![]() doi:10.1201/9781420026399.pt4īrufau G, Canela MA, Rafecas M (2008) Phytosterols: physiologic and metabolic aspects related to cholesterol-lowering properties. In: Awad AB, Bradford P (eds) Nutrition and cancer prevention. Trautwein E, Duchateau G (2005) Phytosterols. MacKay DS, Jones PJH (2011) Phytosterols in human nutrition: type, formulation, delivery, and physiological function. Ostlund RE Jr (2002) Phytosterols in human nutrition. Ryan E, Galvin K, O’Connor TP, Maguire AR, O’Brien NM (2007) Phytosterol, squalene, tocopherol content and fatty acid profile of selected seeds, grains, and legumes. doi:10.1007/s1174-5Īwad AB, Chan KC, Downie AC, Fink CS (2000) Peanuts as a source of β-sitosterol, a sterol with anticancer properties. Jiang Y, Wang T (2005) Phytosterols in cereal by-products. ![]() Nyström L, Paasonen A, Lampi A, Piironen V (2007) Total plant sterols, steryl ferulates and steryl glycosides in milling fractions of wheat and rye. In: Dutta PC (ed) Phytosterols as functional food components and nutraceuticals. Piironen V, Lampi AM (2003) Occurrence and levels of phytosterols in foods. In: Lai OM, Akoh CC (eds) Healthful Lipids. Moreau R (2005) Phytosterols and phytosterol esters. Therefore, the main aim of this chapter is to provide a contemporaneous overview of the beneficial properties of PS, their mechanism of action, and safety. Nevertheless, the mechanisms by which PS exert their beneficial functions, the physiological relevance of PS, and their potential adverse effects are not yet fully understood. Further, there is a growing body of evidence which supports that they play an important role in the prevention of other diseases such as cancer and atherosclerosis. However, recent studies suggest that the beneficial effects of PS are not only limited to their hypocholesterolemic capacity as they can also act as immunomodulatory, anti-inflammatory, and antidiabetic agents. ![]() The cholesterol-lowering capacity of PS is well documented in animal and human studies. Phytosterols (PS) are plant sterols and stanols widely distributed in plant sources that resemble cholesterol in terms of structure and physiological functions.
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